科研项目: 1.陕西省科技厅,基于融合多模影像和机器人技术的脊柱疾病仿生治疗研究,50万,2023.1.1-2025.12.31,项目负责人。 2.陕西省卫健委,肿瘤转移相关蛋白1通过TRPV通路对细胞分化调控的分子机制,20万,2022.03.08-2024.03.08,项目负责人。 3.陕西省中医药管理局,SAP包裹“秦药”盘龙七片制剂及嗅鞘细胞附载PLC纤维促进脊髓损伤修复的作用及分子机制,20万,2021.10.1-2023.10.31,项目负责人。 4.西安市科技局,SAP复合分子促进脊髓损伤修复的作用及分子机制,10万,2021.10-2023.9,项目负责人。 5.陕西省科技厅科技成果转移与推广计划-获奖成果转化项目,脊柱损伤修复关键技术的推广应用,80万,2020.6.1-2023.12.30,项目负责人。 学术论文: 1.Xiangcheng Gao , Lin Gao, Zhen Chang, Dingjun Hao , Jinpeng Du, Jiayuan Wu , Zhigang Zhao , Xiaobin Yang , Hua Hui, Baorong He , Liang Yan.Case series of unilateral biportal endoscopic-assisted transforaminal lumbar interbody fusion in the treatment of recurrent lumbar disc herniation. Am J Transl Res. 2022,15;14(4):2383-2392. (2022年,通讯作者) 2.Wen Zeng,Hua Hui,Zhongyang Liu,Zhen Chang,Mingbo Wang,Baorong He,Dingjun Hao.TPP ionically cross-linked chitosan/PLGA microspheres for the delivery of NGF for peripheral nerve system repair[J].Carbohydrate Polymers,2021:117684. (2021年,通讯作者) 3.Wen Zeng , Zhen Chang,Zhongyang Liu , Lei Zhu ,Mingbo Wang ,Dingjun Hao, Baorong He. Controlled delivery of bioactive BDNF for potential treatment of peripheral nerve injury[J]. Polymer Degradation and Stability,2020,181:109296. . (2020年,通讯作者) 4.Xiaobin Yang,Haishi Zheng,Yuan Liu,Dingjun Hao,Baorong He,Lingbo Kong. Puerarin for OVX-Induced Postmenopausal Osteoporosis in Murine Model: Systematic Review and Meta-Analysis[J].Current Stem Cell Research & Therapy.2020, 15(1):37-42.(2020年,通讯作者) 5.Baorong He, Xinhua Yin, Dingjun Hao, Xiaobin Yang*. Blockade of IL-6 alleviates bone loss induced by modeled microgravity in mice. Can J Physiol Pharmacol. 2020,98(10):678-683. (2020年,第一作者) 6.Fan Xu, Guanghao Chi, Liang Yan, Wang Jun, Wu Wei, Baorong He. Treg-promoted New Bone Formation Through Suppressing TH17 by Secreting Interleukin-10 in Ankylosing Spondylitis,Spine,2019,44(23): E1349–E1355.(2019年,通讯作者) 7.Chang Liu,Yuan He,Xiaobing Xu,Baorong He.Phospholipase Cγ signaling in bone marrow stem cell and relevant natural compounds therapy.[J].Current stem cell research & therapy, 2019, 14, 107-117.(2019年,通讯作者) 8.Hao Wen, Yuan He, Ke Zhang, Xiaobin Yang, Dingjun Hao, Yonghong Jiang, Baorong He. Mini-review: Functions and Action Mechanisms of PQQ in Osteoporosis and Neuro Injury, Current Stem Cell Research & Therapy, 2019, 14, 145-149.(2019年,通讯作者) 9.Bolong Zheng, Dingjun Hao, Hua Guo, Baorong He.Correlation between the progression of cancer and the expression of matrix metalloproteinase-9 in metastatic spinal tumor [J].Journal of Buon,2018, 23(5):1534-1539. (2018年,通讯作者) 10.Bolong Zheng, Dingjun Hao, Hua Guo , Baorong He. Anterior versus posterior surgical approach for lumbosacral tuberculosis [J]. Journal of International Medical Research, 2018, 46(7):2569-2577 (2018年,通讯作者) 11.Ke Zhang, Jun Lei, Yuan He, Xiaobin Yang, Zhen Zhang, Dingjun Hao, Biao Wang, Baorong He. A flavonoids compound inhibits osteoclast differentiation by attenuating RANKL induced NFATc-1/c-Fos induction[J]. International Immunopharmacology, 2018,61:150-155. (2018年,通讯作者) 12.Xiaobin Yang, Dingjun Hao, Haiping Zhang, Benyin Liu, Ming Yang,Baorong He.Treatment with hydrogen sulfide attenuates sublesional skeletal deterioration following motor complete spinal cord injury in rats [J].Osteoporosis International.2017, 28(2):687-695. (2017年,通讯作者) 13.Liang Yan, Rui Gao ,Yang Liu, Baorong He, Shemin Lv, Dingjun Hao .The Pathogenesis of Ossification of the Posterior Longitudinal Ligament. Aging and Disease, 2017,8(5): 570-582.(2017年,通讯作者) 14.Hao Yang, Cuicui Liu,Bo Chen,Jing An, Rui Zhang, Qian Zhang,Jingjing Zhao,Baorong He, Dingjun Hao.Efficient Generation of Functionally Active Spinal Cord Neurons from Spermatogonial Stem Cells [J].Molecular Neurobiology.2017,.54(1):788-803. (2017年,通讯作者) 15.Hao Yang, Lingling Zhang, Jing An, Qian Zhang, Cuicui Liu, Baorong He, Dingjun Hao.MicroRNA-Mediated Reprogramming of Somatic Cells into Neural Stem Cells or Neurons [J].Molecular Neurobiology.2017, 54(2):1587-1600. (2017年,通讯作者) 16.Dingjun Hao, Cuicui Liu, , Lingling Zhang, Bo Chen, Qian Zhang, Rui Zhang, Jing An, Jingjing Zhao, Mingmei Wu, Yi Wang, Alfred Simental, Baorong He, Hao Yang.Lipopolysaccharide and Curcumin Co-Stimulation Potentiates Olfactory Ensheathing Cell Phagocytosis Via Enhancing Their Activation[J]. Neurotherapeutics.2017, 14(2):502-518. (2017年,通讯作者) 17.Baorong He, Fan Lu, Lingling,Zhang, Hao Yang , Dingjun Hao. An alternative long-term culture system for highly-pure mouse spermatogonial stem cells, J Cell Physiol. 2016, 230(6): 1365~1375 .(2016年,第一作者) 18.Yan Liang , He Baorong , Guo Hua Tuanjiang Liu, Dingjun Hao. The prospective self-controlled study of unilateral transverse process-pedicle and bilateral puncture techniques in percutaneous kyphoplasty. Osteoporosis International, 2016, 27(5):1849-1855.(2016年,通讯作者) 19.Huimin Hu, Hua Hui, Haiping Zhang, Dageng Huang, Zhongkai Liu, Yuanting Zhao, Simin He, Xuefang Zhang, Baorong He, Dingjun Hao.The impact of posterior temporary internal distraction on stepwise corrective surgery for extremely severe and rigid scoliosis greater than 130°.[J].European Spine Journal.2016, 25(2):557-568. (2016年,通讯作者) 20.Xiaobin Yang,Bolong Zheng,Dingjun Hao,Benyin Liu,Liang Yan,Baorong He.Treating Huge Tear-Drop Fracture of Axis With Trapezoidal Bone: A Case Report and Literature Review.[J].Spine.2015, 40(22):E1187-E1190. (2015年,通讯作者) 21.Hao Yang,Baorong He,Dingjun Hao.Biological Roles of Olfactory Ensheathing Cells in Facilitating Neural Regeneration: A Systematic Review[J].Molecular neurobiology.2015,51(1):168-179. (2015年,共同第一作者) 22.Dageng Huang,Simin He,Junwei Pan,Hua Hui,Huimin Hu,Baorong He,Hui Li;Xuefang Zhang,Dingjun Hao.Is the 4 mm height of the vertebral artery groove really a limitation of C1 pedicle screw insertion?.European spine journal,2014, 23(5):1109-1114. (2014年,通讯作者) 23.Dageng Huang,Dingjun Hao,Yonghong Jiang,Yue Cheng,Junwei Pan,Yongqian Qiang,Baorong He,Lixiong Qian.The height for screw index (HSI) predicts the development of C2 nerve dysfunction associated with C1 lateral mass screw fixation for atlantoaxial instability.[J].European spine journal.2014, 23(5):1092-1098. (2014年,通讯作者) 24.Liang Yan, Zhen Chang, Zhengwei Xu, Tuanjiang Liu, Baorong He, Dingjun Hao.Biomechanical effects of bone cement volume on the endplates of augmented vertebral body: a three-dimensional finite element analysis[J].Chinese Medical Journal.2014, 127(1):79-84. (2014年,通讯作者) 25.Guodong Feng,Baorong He, Fan Lu.Fibroblast Growth Factor 4 Is Required but not Sufficient for the Astrocyte Dedifferentiation[J].Molecular Neurobiology.2014, 50(3):997-1012.(2014年,共同第一作者) 26.Liang Yan, Hua Guo, Zhengwei Xu, Tuanjiang Liu, Xiaodong Wang, Baorong He, Dingjun Hao.KumaFix fixation for thoracolumbar burst fractures: a prospective study on selective consecutive patients.[J].Chinese medical journal.2014,127(11):2001-2006. (2014年,通讯作者) 27.Baorong He,Liang Yan, Hua Guo, Tuanjiang Liu, Xiaodong Wang,Dingjun Hao.The difference in superior adjacent segment pathology after lumbar posterolateral fusion by using 2 different pedicle screw insertion techniques in 9-year minimum follow-up[J].Spine.2014, 39(14):1093-1098. (2014年,第一作者) 28.Liang Yan,Renqi Jiang,Baorong He,Tuanjiang Liu,Dingjun Hao.A comparison between unilateral transverse process-pedicle and bilateral puncture techniques in percutaneous kyphoplasty[J].Spine.2014, 39(26):B19-B26. (2014年,通讯作者) 29.Baorong He ,Songtao Xie, Mingmei Wu, Hao Yang, Dingjun Hao. Phagocytic Removal of Neuronal Debris by Olfactory Ensheathing Cells Enhances Neuronal Survival and Neurite Outgrowth via p38MAPK Activity, Mol Neurobiol, 2014, 49(3): 501~1512.(2014年,第一作者) 30.Baorong He , Liang Yan, Qinpeng Zhao Zhen Chang; Dingjun Hao.Self-designed posterior atlas polyaxial lateral mass screw-plate fixation for unstable atlas fracture, Spine J, 2014, 14(12): 2892~2896.(2014年,第一作者) 31.Baorong He , Liang Yan, Zhengwei Xu , Hua Guo ,Tuanjiang Liu ,Dingjun Hao. Treatment strategies for the surgical complications of thoracic spinal stenosis: a retrospective analysis of twohundred and eighty three cases, International orthopaedics,2014,38(1):117-122.(2014年,第一作者) 32.Baorong He, Liang Yan, Zhengwei Xu, Zhen Chang, Dingjun Hao. The causes and treatment strategies for the postoperative complications of occipitocervical fusion: a 316 cases retrospective analysis, Eur Spine J,2014,23(8):1720-1724.(2014年,第一作者) 33.Liang Yan, Zhen Chang, Yang Liu, Yibing Li, Baorong He, Dingjun Hao.A single nucleotide polymorphism in the human bone morphogenetic protein-2 gene (109T > G) affects the Smad signaling pathway and the predisposition to ossification of the posterior longitudinal ligament of the spine[J]. Chinese Medical Journal ,2013, 126(6):1112-1118. (2013年,通讯作者) 34.Liang Yan, Zhen Chang, Yang Liu, Baorong He, Dingjun Hao.Primary spinal melanoma: a case report and literature review[J].Chinese Medical Journal,2012,,125(22):4138-4141.(2012年,通讯作者) 35.弓伊宁,王江, 贺宝荣. 骨质疏松性椎体骨折开放手术治疗的相关问题[J]. 中华创伤杂志,2022,38(2):97-100. (2022年,专家论坛,通讯作者) 36.李庆达,贺园, 贺宝荣. 骨质疏松性胸腰椎骨折椎体强化术后并发骨水泥渗漏的若干问题[J]. 中华创伤杂志,2022,38(3):193-197. (2022年,专家论坛,通讯作者) 37.许正伟,郝定均, 贺宝荣. 《症状性陈旧性胸腰椎骨质疏松性骨折手术治疗临床指南》要点解读[J]. 中华创伤杂志,2022,38(4):297-300. (2022年,专家论坛,通讯作者) 38.贺宝荣,,郑博隆. 骨质疏松性胸腰椎骨折的诊断和分型方法解析[J]. 中华创伤杂志,2021,37(3):205-209. (2021年,专家论坛,通讯作者) 39.贺宝荣.,郑博隆. 骨质疏松性胸腰椎骨折的阶梯化和精准化治疗[J]. 中华创伤杂志,2021,37(6):488-493. (2021年,专家论坛,通讯作者)、 40.郝定均,郑博隆, 贺宝荣.. 骨质疏松性胸腰椎骨折的若干问题讨论[J]. 中华创伤骨科杂志,2021,23(1):15-19. (2021年,专家论坛,通讯作者) 41.贺宝荣.重视急性症状性胸腰椎骨质疏松性骨折的诊断和治疗[J]. 中华创伤杂志,2020,36(3):212-215. . (2020年,专家论坛,通讯作者) 42.贺宝荣.郑博隆. 中国脊髓损伤规范化治疗和修复机制研究概况[J]. 中华创伤杂志,2020,36(4):289-292. . (2020年,专家论坛,通讯作者) 43. 贺宝荣.干细胞移植治疗脊髓损伤的机制及其临床应用的相关问题探讨[J].中华创伤杂志.2019,35(7):593-596. (2019年,专家论坛,第一作者) 44.贺宝荣,郑博隆.骶髂螺钉治疗不稳定骶骨骨折相关问题探讨[J].中华创伤杂志.2018,34(8):680-683. (2018年,第一作者,专家论坛) 45.贺宝荣,郝定均.上颈椎骨折内固定技术相关问题探讨[J].中华创伤杂志.2017,33(4):300-304. (2017年,第一作者,专家论坛) 获 奖: 1.2024年03月,荣获陕西省科技进步二等奖,项目名称《严重脊柱结核修复的关键技术创新与推广》; 2.2023年8月,荣获教育部科技进步一等奖,项目名称《脊柱脊髓损伤综合救治与康复重建体系的建立和推广》; 3.2020年04月 荣获陕西省科技进步奖一等奖,项目名称:《骨质疏松性脊柱骨折精准化诊疗新体系的创立与推广》; 4.2018年12月 荣获国家科技进步奖二等奖,项目名称:《严重脊柱创伤修复关键技术的创新与推广》; 5.2016年02月 荣获陕西省科学技术奖一等奖,项目名称:《脊柱损伤修复关键技术的基础研究与临床应用》; 6.2012年09月 荣获陕西省科学技术奖二等奖,项目名称:《寰枢椎形态学研究及其临床应用》; 7.2010年01月 荣获陕西省科学技术奖二等奖,项目名称:《钉棒系统与钩棒系统矫正脊柱侧凸的生物力学与临床研究》; 8.2007年02月 荣获陕西省科学技术奖一等奖,项目名称:《脊柱脊髓损伤的基础与临床研究》; 9.2006年06月 荣获陕西省科学技术奖二等奖,项目名称:《上颈椎脱位失稳并高位脊髓不全损伤的外科治疗》; 10.2005年9月 荣获西安市科学技术奖一等奖,项目名称:《脊柱脊髓损伤的基础与临床研究》; 专 利: 1.发明专利:一种符合脊柱颈胸段解剖学和生物力学的专用固定装置,专利号:ZL201910428689.0,授权日期:2022年5月3日 2.发明专利:一种断裂骨钉的取出装置,专利号:ZL202010482482.4,授权日期:2021年10月1日; 3.发明专利 :骨科临床用医用钢板预弯装置,专利号:ZL201510490647.1,授权日期:2017年7月21日; 4.发明专利:脊柱拉伸装置,专利号:ZL201410476926.8,授权日期:2016年8月24日; 5.实用新型专利:寰椎后弓固定器,专利号:ZL201220082543.9,授权日期:2012年10月24日; 6.实用新型专利:椎体截骨刀,专利号:ZL200820029581.1,授权日期:2009年3月25日; 7.实用新型专利:椎弓根弹性开路锥,专利号:ZL200820029445.2,授权日期:2009年3月4日。 |