科研项目: 1.国家自然科学基金委员会地区科学基金项目:基于化学酶法对癌症细胞表面黏蛋白上截短型O-聚糖的快速识别与分析方法研究 2.陕西省卫生健康委员会青年项目:高选择性卵巢癌早期检测探针的构建与临床应用研究 3.4001百老汇会员登录博士科研启动项目:糖工程技术对硫酸化糖修饰的研究 学术论文: 1.Sun L, Fu H, Li Y, Duan X, Li Z. Rapid Recognition and Isolation of Live Colon Cancer Stem Cells by Using Metabolic Labeling of Azido Sugar and Magnetic Beads. Anal Chem. 2016 Apr 5;88(7):3953-8. (一区) 2.Sun L, Konstantinidi A, Ye Z, Nason R, Zhang Y, Büll C, Kahl-Knutson B, Hansen L, Leffler H, Vakhrushev SY, Yang Z, Clausen H*, Narimatsu Y*. Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins. J Biol Chem. 2022 Feb;298(2):101382. (二区TOP ) 3.Sun L, Zhang Y, Li W, Zhang J*, Zhang Y*. Mucin Glycans: A Target for Cancer Therapy. Molecules. 2023 Oct 11;28(20):7033. (二区TOP ) 4.Zhang Y, Sun L*, Lei C, Li W, Han J, Zhang J, Zhang Y*. A Sweet Warning: Mucin-Type O-Glycans in Cancer. Cells. 2022 Nov 18;11(22):3666. (二区) 5.Ma J, Sun L, Gao F, Zhang S, Zhang Y, Wang Y, Zhang Y, Ma H. A Review of Dual-Emission Carbon Dots and Their Applications. Molecules. 2023 Dec 17;28(24):8134. (二区TOP,共同第一作者) 6.Willems AP, Sun L, Schulz MA, Tian W, Ashikov A, van Scherpenzeel M, Hermans E, Clausen H, Yang Z, Lefeber DJ. Activity of N-acylneuraminate-9-phosphatase (NANP) is not essential for de novo sialic acid biosynthesis. Biochim Biophys Acta Gen Subj. 2019 Oct;1863(10):1471-1479. (三区,共同第一作者) 7.Zhang Y, Zhang J, Sun L*, Tian R, Ma H*. Ratiometric detection of propafenone hydrochloride with one‑pot synthesized dual emissive carbon dots. Chem. Pap. 2022 Sep;77: 375–383. (四区) 专 利: 孙凌波,李文彦,张越诚,张雨晗;一种聚糖结构教学模型展示装置;专利号:ZL 2023 2 0640355.1 |