科研项目: 1. 陕西省科技厅,2023.01-2024.12,在研,主持 ; 2. 陕西省卫健委,2022.01-2023.12,结题,主持; 3. 陕西省教育厅,结题,主持; 4. 延安市科技局,2023.05-2025.05,在研,主持; 5. 国家自然科学基金委员会,重点项目,2020.01-2024.12,297 万元,在研,参与; 学术论文: 1.X Bai,Y Yang,Y Luo,D Zhang,T Zhai,Q Hu,N Zhang,Q Dai,J Liang,H Bian ,Liu XL*.Design and synthesis of sulfonamide phenothiazine derivatives as novel ferroptosis inhibitors and their therapeutic effects in spinal cord injury[J].Bioorganic Chemistry, 2024, 148.DOI:10.1016/j.bioorg.2024.107458.(通讯作者) 2.Yu Y, Zhang L, Zhang D, Dai Q, Hou M, Chen M, Gao F, Liu XL*. The role of ferroptosis in acute kidney injury: mechanisms and potential therapeutic targets. Mol Cell Biochem. 2024 Jun 28. doi: 10.1007/s11010-024-05056-3.(通讯作者) 3.Yang W#, Liu X#, Song C#, Ji S, Yang J, Liu Y, You J, Zhang J, Huang S, Cheng W, Shao Z, Li L, Yang S.* Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model[J]. Eur J Med Chem. 2021 Jan 1;209:112842.(共同作者) 4.Luo Y, Bai XY, Zhang L, Hu QQ, Zhang N, Cheng JZ, Hou MZ, Liu XL*. Ferroptosis in Cancer Therapy: Mechanisms, Small Molecule Inducers, and Novel Approaches. Drug Des Devel Ther. 2024 Jun 21;18:2485-2529. doi: 10.2147/DDDT.S472178. PMID: 38919962; PMCID: PMC11198730.(通讯作者) 获 奖: 第九届全国大学生基础医学创新研究暨实验设计论坛总决赛--铜奖1项(指导老师) 第十届全国大学生基础医学创新研究暨实验设计论坛总决赛--银奖3项(指导老师) 陕西省教学成果奖二等奖(排名5) |