科研项目: 1.陕西省自然科学基金项目(2014JM4039),SIRT3调控Pyroptosis 在脑缺血后炎症反应中的作用及机制(2014.01-2016.12,4万元,负责人,结题) 2.陕西省重点研发计划(2018SF-035),颅内动脉粥样硬化/支架后再狭窄与内皮祖细胞相关性及SIRT3增强EPCs活性机制 的研究(2018.6-2020.6,12万元,负责人,结题) 3.西安市创新能力强基计划-学科能力建设项目(21YXYJ0004),西安地区脑卒中绿色通道救治体系标准化及应用研究(2021,10-2024,09,40万元,负责人,在研) 4.陕西省自然科学基础研究计划项目(2022JM-452),光遗传控制线粒体自噬调控GPX4介导铁死亡在脑缺血再灌注损伤中作用和机制(2022.01-2023.12,10万元,负责人,在研) 5.中国卒中学会脑血管病启航基金项目,依达拉奉右崁醇改善慢性脑低灌注认知障碍炎症机制研究(2021.01-2023.12,10万元,负责人,在研) 学术论文: 1.Mingze Chang, Bei Zhang,Ye Tian,et al.AGEs Decreased SIRT3 Expression and SIRT3 Activation Protected AGEs-Induced EPCs’ Dysfunction and Strengthened Anti-oxidant Capacity.Inflammation,2017,40(2):473-475.(第一作者,IF=4.5) 2.Nannan Han, Xiaobo Zhang, Yu Zhang, Yu Liu, Haojun Ma, Hanming Ge, Yanfei Wang, Shilin Li, Xudong Yan, Tengfei Li, Yulun Wu, Juan Ma, Wenzhen Shi, Gejuan Zhang, Ye Tian ,and Mingze Chang. Endovascular thrombectomy versus medical management on outcomes with infarct volumes more than 70 mL. Ann Clin Transl Neurol. 2024 Aug;11(8):2040-2048.(通讯,IF=4.4) 3.Nannan Han, Xiaobo Zhang, Yu Zhang, Yu Liu, Yongqin Zhang, Haojun Ma, Hanming Ge, Shilin Li, Xiao Zhang, Xudong Yan, Tengfei Li, Bin Gao, Chengxue Du, Xinchao Ji, Wenzhen Shi, Ye Tian, and Mingze Chang.Nomogram to predict unfavorable outcome of endovascular thrombectomy for large ischemic core.Ann Clin Transl Neurol. 2023 Aug; 10(8): 1353–1364.(通讯,IF=4.4) 4.Shilin Li , Yu Zhang , Xiaobo Zhang , Gejuan Zhang , Nannan Han , Haojun Ma , Hanming Ge , Yong Zhao , Leshi Zhang , Yanfei Wang , Wenzhen Shi , Xiaojuan Ma , Yizhuo Tian , Yixuan Xiao , Yinuo Niu , Lin Qiao , Mingze Chang .The Functional Prognosis of Rescue Conscious Sedation During Mechanical Thrombectomy on Patients with Acute Anterior Circulation Ischemic Stroke: A Single-Center Retrospective Study.Neurol Ther 2023 ;12(5):1777-1789.(通讯,IF=3.9) 5.Xiaobo Zhang , Nannan Han , Yu Zhang , Wenting Yuan , Shangguang Kan , Gejuan Zhang , Haojun Ma , Hanming Ge , Chengxue Du , Yanjun Gao , Shilin Li , Xudong Yan , Wenzhen Shi , Ye Tian , Mingze Chang.Predicting 3-month Functional Outcome After Endovascular Thrombectomy in Patients with Anterior Circulation Occlusion with an Arterial Transit Artifact Grading System.Clin Neuroradiol. 2023 Dec 5.doi: 10.1007/s00062-023-01362-3.(通讯,IF=2.4) 6.Nannan Han, Gejuan Zhang, Shiyao Yang, Haojun Ma,Hanming Ge, Xiao Zhang, Shilin Li, Yanfei Wang,Xiaonan Fan, Yanling Yin, Yanjun Gao, Wenzhen Shi,Xiaobo Zhang, Mingze Chang* and Ye Tian*.The relationship between vertebrobasilar artery calcification and intracranial atherosclerosis-related occlusion in thrombectomy. Front. Neurol. 13:965362.doi: 10.3389/fneur.2022.965362(共同通讯,IF=2.7) 7.Li S, Yang S, Zhang X, Zhang Y, Zhang J, Zhang X, Li W, Niu X, Shi W, Zhang G, Chang M*, Tian Y*. Impact of MMP2 rs243849 and rs14070 genetic polymorphisms on the ischemic stroke susceptibility in Chinese Shaanxi population. Front Neurol,2022 25;13:931437(共同通讯,IF=2.7) 8.Han, N, Zhang, G, Li, Y, Ma, H, Ge, H, Zhang, X, Zhao, Y, Li, S, Zhang, L, Gao, Y, Shi, W, Yan, P, Li, W, Chang, M*, & Tian, Y*. Hyperattenuated Lesions on Immediate Non-contrast CT After Endovascular Therapy Predict Intracranial Hemorrhage in Patients With Acute Ischemic Stroke: A Retrospective Propensity Matched Study. Frontiers in neurology, 2021,12, 664262(共同通讯,IF=2.7) 9.Gao, B., Wang, S., Li, J., Han, N., Ge, H., Zhang, G., & Chang, M. . HMGB1, angel or devil, in ischemic stroke. 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(通讯作者) 21.葛晗明,张静,严晶晶,韩楠楠,马浩钧,高燕军,常明则. 急性颈内动脉串联闭塞血管内治疗术后凸面蛛网膜下腔出血一例 [J]. 中华老年心脑血管病杂志,2023,02:207-208. (通讯作者) 获 奖: 参与获得西安市科技进步奖二等奖(2011-2-29-R6) 西安市科技进步奖三等奖(2015-3-20-R6) 陕西省科技进步奖三等奖(13-3-96-R5) 陕西高等学校科学技术二等奖(13Y07) 西安市第十七届自然科学优秀学术论文一等奖(20181140361) 西安市第十七届自然科学优秀学术论文二等奖(20182100231) |