科研项目: 1. LFA-1/Syk交互协同RANKL/NF-κB信号通路调控破骨细胞分化的机制研究,国家青年自然基金(81802167),课题主持人; 2. LFA-1协同 RANKL信号通路调控破骨细胞分化的机制研究,陕西省自然科学基础研究计划项目(2019JM-197),课题主持人; 3. 新型颈椎后路椎管扩大术及其内植物的研发与有效性分析,陕西省重点研发计划-高校联合项目(2020GXLH-Y-003),课题主持人; 4. 一种新型颈椎后路内固定系统用于治疗多节段颈椎病,青年科技新星项目(2022KJXX-64),课题主持人; 5. 新型掺锶和锌阿仑膦酸钠水凝胶复合生物支架修复合并骨质疏松骨缺损的机制研究,西安市面上培育项目(2024ms11),课题主持人。 学术论文: 1.Guo J, Bai Y, Li L, Wang J, Wang Y, Hao D, Wang B(通讯作者). A Comparative Study of 2 Techniques to Avoid Bone Cement Loosening and Displacement After Percutaneous Vertebroplasty Treating Unstable Kummell Disease. Neurospine. 2024 Jun;21(2):575-587. 2.Zhan Y, Bao C, Yang H, Li L, Yan L, Kong L, Hao D, Wang B(通讯作者).Biomechanical analysis of a novel bone cement bridging screw system combined with percutaneous vertebroplasty for treating Kummell's disease. Front Bioeng Biotechnol. 2023;11:1077192. 3.Wang J, Miao J, Zhan Y, Duan Y, Wang Y, Hao D, Wang B(通讯作者). Spine Surgical Robotics: Current Status and Recent Clinical Applications. Neurospine. 2023;20(4):1256-1271. 4.Zhan Y, Kang X, Gao W, Zhang X, Kong L, Hao D, Wang B(通讯作者).Efficacy analysis of one-stage posterior-only surgical treatment for thoracic spinal tuberculosis in the T4-6 segments with minimum 5-year follow-up. Sci Rep. 2022;12(1):149. 5.Wang Y, Zhan Y, Yang H, Guo H, Zhang H, Zhao Q, Hao D, Wang B(通讯作者). A novel anatomic titanium mesh cage for reducing the subsidence rate after anterior cervical corpectomy: a finite element study[J]. Sci Rep. 2021;11(1):15399. 6.Wang B(第一作者),Zhan Y, Bai Y, Kong L, Li L, Zhang H, He S, Hao D. Biomechanical analysis of a novel bone cement bridging screw system for the treatment of Kummell disease: a finite element analysis. Am J Transl Res. 2022;14(10):7052-7062. 7.Wang B(第一作者), Zhan Y, Yan L, Hao D. How zoledronic acid improves osteoporosis by acting on osteoclasts[J]. Front Pharmacol, 2022;13:961941. 8.Wang B(第一作者), Wang Y, Hao D. Current Study of Medicinal Chemistry for Treating Spinal Tuberculosis [J]. Current Medicinal Chemistry, 2021,28(25):5201-5212. 9.Wang B(第一作者), Wen H, Smith W, Hao D, He B, Kong L. Regulation effects of melatonin on bone marrow mesenchymal stem cell differentiation[J]. J Cell Physiol, 2019,234(2):1008-1015. 10.Wang B(第一作者), Hao D, Zhang Z, Gao W, Pan H, Xiao Y, He B, Kong L. Inhibition effects of a natural inhibitor on RANKL downstream cellular signalling cascades cross-talking[J]. J Cell Mol Med, 2018,22(9):4236-4242. 获 奖: 1. 骨质疏松性脊柱骨折精准化诊疗新体系的建立与推广,获陕西省科技进步奖一等奖(编号2019-J-4453-1-R09),陕西省人民政府,2020年; 2. 陕西省青年科技新星(编号2022SR5068号),陕西省科学技术厅,2022年; 3. 严重脊柱结核修复的关键技术创新与推广,获陕西省科技进步奖二等奖(编号2023-J-234558-2-R02),陕西省人民政府,2024年。 专 利: 1.一种椎体增强桥接器系统(发明专利) 专利号:ZL 202410555948.7; 2.INTEGRATED TARGETED KYPHOPLASTY SYSTEM(美国发明专利) 专利号:US 11,744,627 B2; 3.一种棘突间融合装置(实用新型专利) 专利号:ZL 202022148350.6; 4.一种颈椎后路椎管扩大术用内固定系统(实用新型专利) 专利号:ZL 201820610498.7; 5.腰椎后路椎间融合系统(实用新型专利) 专利号:ZL 201920411106.9; 6.一体式靶向椎体后凸成形系统(实用新型专利) 专利号:ZL 201921341486.X; 7.一种椎体骨水泥注射装置(实用新型专利) 专利号:ZL 201921341953.9; 8.一种颈椎椎间融合系统(发明专利) 专利号:ZL 201610201237.5); 9.骨折复位辅助仪(发明专利) 专利号:ZL 201610173517.X; 10.骨修复材料及其制备方法(发明专利) 专利号:ZL 201510638536.0。 |