科研项目: 1. 国自然自然科学基金(82360223):FCHSD2调控小鼠耳蜗外毛细胞静纤毛维持的分子机制研究 2. 校级博士科研启动项目(A类)(205040404):腺相关病毒(AAV)介导的渐进性听力损失基因治疗研究 学术论文: 1. Zhai X, Du H, Shen Y, Zhang X, Chen Z, Wang Y, Xu Z*: FCHSD2 is required for stereocilia maintenance in mouse cochlear hair cells. J Cell Sci 2022, 135(16). 2. Zhai X, Shen Y, Zhang X, Li T, Lu Q, Xu Z*: FCHSD2 cooperates with CDC42 and N-WASP to regμlate cell protrusion formation. Biochim Biophys Acta Mol Cell Res 2021:119134. 3. Zhai X#, Liu C#, Zhao B, Wang Y, Xu Z*: Inactivation of cyclin-dependent kinase 5 in hair cells causes hearing loss in mice. Front Mol Neurosci 2018, 11:461. 4. Liu C, Zhai X, Zhao B, Wang Y, Xu Z*: Cyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulation. Sci Rep 2017, 7:40979. 5. Liu C, Zhai X, Du H, Cao Y, Cao H, Wang Y, Yu X, Gao J, Xu Z*: Sorting nexin 9 (SNX9) is not essential for development and auditory function in mice. Oncotarget 2016, 7(42):68921-68932. |