科研项目: 1.HECW2 通过泛素化激活AKT/mTOR 信号通路介导结直肠癌生长转移的机制研究(国家自然科学基金,在研, 参与) 2.生活环境的颜色与机体肠道微生物组的相关性研究(博士科研启动项目,在研,主持) 3.家蚕BmREEP 基因在杆状病毒入侵过程中的作用机制研究(高层次人才引进计划,结题,主持) 4.家蚕类胡萝卜素转运相关蛋白对类胡萝卜素的转运功能初探(重庆市基础与前沿研究计划项目,结题,参与) 5.家蚕核型多角体病毒lef-11 基因对病毒增殖的调控研究(国家自然科学基金项目,结题,参与) 6.桑树种子对重金属镉胁迫的应激机制研究(陕西省自然科学基础研究计划,结题,主持) 学术论文: 1.Combined Effect of Cameo2 and CBP on the Cellular Uptake of Lutein in the Silkworm, Bombyx mori. PLOS one 2014, 9(1):e86594. 2.BmREEPa is a novel gene that facilitates BmNPV entry into silkworm cells. PLOS one 2015, 10(12):e0144575. 3.BmNHR96 participate BV entry of BmN-SWU1 cells via affecting the cellular cholesterol level, BBRC, 2016,12.061. 4.A newly discovered member of the Atlastin family,BmAtlastin-n, has an antiviral effect against BmNPV in Bombyx mori, SR, 2016, 6:28946. 5.Transgenic RNAi of BmREEPa in Silkworms can enhance the Resistance of Silkworm to Bombyx mori Nucleopolyhedrovirus, BBRC, 2017, 01.017. 6.Bombyx mori protein BmREEPa and BmPtchd could form a complex with BmNPV envelope protein GP64, BBRC, 2017, 490 (4). 7.Identification and Characterization of the BmCyclin L1-BmCDK11A/B complex in relation to cell cycle regulation, Cell Cycle, 2017, 16 (9). 8.In vivo RNA interference of BmNHR96 enhances the resistance of transgenic silkworm to BmNPV. BBRC, 2017.493(1). 9.A Novel Gene Bombyx mori Carotenoid Oxygenases and Retinal Isomerase (BmCORI) Related to β-Carotene Depletion,Biochemical Genetics,2020,58:509-517 10.Geminin is essential for DNA re-replication in the silk gland cells of silkworms, Exp Cell Res. 2022,410(1) 11.The dual roles of three MMPs and TIMP in innate immunity and metamorphosis in the silkworm, Bombyx mori, FEBS J,2022,289(10) 12.家蚕CDK11与RNPS1和9G8相互作用的鉴定[J],中国农业科学 2017,50(22):4398-4407. 13.山羊钴胺素转运蛋白受体基因CD320的克隆与表达模式[J], 农业生物技术学报 2018,26(8):1342-1350. 专 利: 1.家蚕受体表达增强蛋白BmREEPa 及其重组表达载体和应用,CN201510065509.9 |